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Towards Adaptive Radiotherapy (ART) for Cervical Cancer: CT-study of the effect of full and empty bladder on the position of the uterus

Completed
Conditions
10038594
cervical cancer
Registration Number
NL-OMON47258
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
33
Inclusion Criteria

Adult women with inoperable cervical cancer

Exclusion Criteria

* Inability of the patient to provide informed consent or legally incompetent/incapacitated to do so,
* Pregnancy
* Patients with a hip prosthesis (due to scatter on CBCT and heating in MRI)
* Cardiac arrythmias, pacemaker/ICD, neurostimulator, insuline pump, cochlear implants, glaucoma, myasthenia gravis
* Metal implants in region of interest, metal implants before 1995
* Intracranial clips before 1995
* Occupation as metal worker
* Claustrofobia
* Tricyclic antidepressants

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Variability of uterus position under influence of filling of the urinary<br /><br>bladder.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Daily variation in bladder filling (with cone-beam CT), tumorlokalization (with<br /><br>fiducial gold markers), and tumour response (weekly MRI-scans).</p><br>
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