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Development of an ointment for the treatment of cutaneous Leishmaniasis

Phase 1
Conditions
cutaneous leishmaniasis
Registration Number
RBR-249zxxh
Lead Sponsor
niversidade Federal do Amazonas - UFAM
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

Age between 18 and 70 years; both genders; Individuals considered healthy after initial clinical and laboratory evaluation; Agreement and voluntary signature of the free and informed consent form

Exclusion Criteria

Individuals who present alterations in the pre-treatment clinical and/or laboratory assessment; History of visceral leishmaniasis or American cutaneous leishmaniasis; Liver or kidney dysfunction, diabetes or heart disease; Allergy to the experimental treatment; Pregnant and lactating women; Alcoholics, smokers or those using medication; Patients with chronic diseases and/or infectious diseases such as tuberculosis, leprosy, human immunodeficiency virus, visceral leishmaniasis or American cutaneous leishmaniasis, among others; Patients with a medical history of visceral leishmaniasis or American cutaneous leishmaniasis; Inability or refusal to sign the informed consent form or inability to comply with the experimental protocol

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
It is expected with this project that the pharmaceutical compound in topical formulation with the purpose of combating the Leishmaniasis parasite is safe, with no adverse effect in phase 1 tests, thus being able to proceed to phase 2 tests.
Secondary Outcome Measures
NameTimeMethod
Secondary outcomes are not expected
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