NCT01425840已完成1 期
Efficacy of Liposome Lidocaine Gel for Topical Anesthesia in the Palatal Mucosa
University of Campinas, Brazil1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2008年3月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- The efficacy of topical anesthetics on the oral mucosa.
研究概览
简要总结
This blinded cross-over study aimed to evaluate the efficacy of topical liposome-encapsulated lidocaine on oral mucosa.
详细描述
This blinded cross-over study aimed to evaluate the efficacy of topical liposome-encapsulated 2,5 and 5% lidocaine gel formulations on the palatal mucosa.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Health Services Research
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Volunteers were free from cardiac, hepatic, renal, pulmonary, neurological, gastrointestinal and haematological diseases, psychiatric disorders and allergy to local anesthetics
研究组 & 干预措施
Liposomal lidocaine, topical anesthesia
Experimental
Efficacy of Liposomal lidocaine in topical anesthesia.
干预措施: Lidocaine (Drug)
结局指标
主要结局
The efficacy of topical anesthetics on the oral mucosa.
时间窗: 10 seconds
The topical formulations were kept in the palatal mucosa during 2 min. The efficacy of the topical formulations was assessed after a pinprick and a local anesthetic injection on the application site.
次要结局
未报告次要终点
研究者
研究点 (1)
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