Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study - The ACCESS IV Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Ischemic Heart Disease
- Sponsor
- Aarhus University Hospital Skejby
- Enrollment
- 400
- Locations
- 1
- Primary Endpoint
- Neurophysiological measurements
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
Evaluation of potential nerve damage after radial CAG/PCI.
Detailed Description
Prospective patients scheduled for radial CAG/ PCI will be enrolled in the study. Prior to the procedure, sensory and motor nerve examination is performed at the wrists in both arms / hands. The examination is performed on both the median nerve and the ulnar nerve. Each patient acts as their own control. The nerve test is repeated bilaterally 1 month after the procedure. This creates 2 groups, A and B. Patients will be asked to complete 2 questionnaires in relation to hand and arm symptoms. The patients ability to perform certain activities before and after the CAG/PCI procedure are also addressed. In addition, a diagnostic tool (Katz chart) will be completed, also before and after the CAG/PCI procedure. Hypothesis: Radial access is associated with an increased risk of pain and an increased incidence of nerve damage similar to the median nerve at the carpal tunnel or the ulnar nerve at the Guyon's canal.
Investigators
Christian Juhl Terkelsen
Professor, Professor, Chief Physician, PhD.
Aarhus University Hospital Skejby
Eligibility Criteria
Inclusion Criteria
- •The patient must be able to give informed consent
Exclusion Criteria
- •Pregnancy
- •Negative Barbeau test
Outcomes
Primary Outcomes
Neurophysiological measurements
Time Frame: Aprox 1 hour
The primary aim is the incidence/presence of electrofysiological signs of median and/or ulnar nerve lesion at the wrist and the presence of carpaltunnel syndrom. The electrodiagnosis of carpaltunnelsyndrom will be determined from the clinical picture and signs of prolonged distal motor lantency and reduced motor and sensory nerveconduction velocity across the wrist and/or reduced amplitudes of the median nerve and normal ulnar nerve at the wrist.
Secondary Outcomes
- Severity of hand symptoms and hand dysfunction(10 min)