Efficacy of Buffered Articaine in Maxillary Third Molar Extractions

A randomized double blind split mouth interventional study will be conducted with an aim to examine whether buffering articaine will help in terms of pain at injection site, onset of anesthesia, duration of anesthesia, post extraction pain. the objectives of the study were to assess the pain, onset of anesthesia,  duration of anesthesia, and post extraction pain at the injection site of Articaine and Buffered Articaine groups. and to compare pain at the site of injection, onset of anesthesia, duration of anesthesia, and post extraction pain between Articaine and Buffered Articaine groups. A total of 52 patients reporting to the department of oral and maxillofacial surgery during the study period for maxillary third molar extractions will be selected based on inclusion and exclusion criteria Study will be explained and written informed consent will be obtained from the participants and patients will be randomly assigned to one of the two groups (Group-1 Articaine, Group-2 Buffered Articaine) by coin toss method. In Group 1 Articaine will be administered by buccal infiltration (0.9ml) alone and extraction was done and in Group 2 Buffered Articaine will be administered by buccal infiltration (0.9ml) and extraction was done and pain at injection and onset of anesthesia will be assessed immediately after injection and surgical procedure will be carried out by single surgeon later duration of anesthesia, post extraction pain will be assessed post operatively after 3 hours. Statistical analysis will be done using descriptive and inferential statistics that include Dependent t test / Wilcoxon signed rank test to compare variables between both the groups.