Comparison study of bone graft with or without injectable platelet rich fibrin in gum disease.
- Conditions
- Chronic periodontitis,
- Registration Number
- CTRI/2020/03/023781
- Lead Sponsor
- UMA P NAIR
- Brief Summary
This study was an interventional study done to compare the efficacy of i-PRF with bone graft and bone graft alone in the treatment of mandibular grade II furcation defect. A total of 12 patients were randomized using the lottery method into test and control groups.
Test group (A): i-PRF with bone graft following open flap debridement
Control group (B): only bone graft following open flap debridement
The bone graft used were commercially available hydroxyapatite. This was a 9 months study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 16
1)Systemically healthy patients within the age group of 30-55 years both male and female 2)Clinical and radiographic evidence of mandibular buccal furcation defect ≥ 3mm 3)Vital tooth 4)Vertical probing depth ≥5mm, Horizontal probing depth ≥ 3mm.
- 1.Systemic illness such as diabetes, cardiovascular diseases, insufficient platelet count (<200,000/ mm3) or immunocompromised patients.
- 2.Patients using tobacco in any form 3.Pregnant or lactating mother 4.Known allergy to any of the material 5.Patients on any medication 6.Patients on antibiotic therapy within last 3 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The bone regenerative effects of i-PRF with bone graft in mandibular grade II furcation defects Baseline, 3 months, 6 months and 9 months post treatment
- Secondary Outcome Measures
Name Time Method Improvements in clinical and radiographical parameters At baseline,3,6 & 9 MONTHS
Trial Locations
- Locations (1)
JSS DENTAL COLLEGE AND HOSPITAL
🇮🇳Mysore, KARNATAKA, India
JSS DENTAL COLLEGE AND HOSPITAL🇮🇳Mysore, KARNATAKA, IndiaUMA P NAIRPrincipal investigator8075530631umapn17@gmail.com