Feasibility study of a hyperspectral imaging system in detection of human skin perfusion and oxygenatio
Completed
- Conditions
- tissue oxygenation, tissue perfusion
- Registration Number
- NL-OMON28750
- Lead Sponsor
- eiden University Medical Center (LUMC)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 8
Inclusion Criteria
Healthy volunteers, 18 to 45 years of age, inclusive. Healthy status is defined by absence of evidence of any active or chronic disease following a detailed medical and surgical history.
-Body mass index (BMI) between 18 and 30 kg/m2, inclusive, and with a minimum weight of 50 kg.
Exclusion Criteria
-History or symptoms of any significant disease including (but not limited to), neurological, psychiatric, endocrine, cardiovascular, respiratory, gastrointestinal, hepatic, or renal disorder.
-Systolic blood pressure (SBP) greater than 140 or less than 90 mm Hg, and diastolic blood pressure (DBP) greater than 90 or less than 50 mm Hg.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method feasibility, applicability, and reproducibility of a novel hyperspectral camera system in perfusion and oxygenation detection in healthy volunteers.
- Secondary Outcome Measures
Name Time Method Hyperspectral measures of: <br /><br>1.basal blood flow / oximetry<br /><br>2.blood flow /oximetry upon occlusion-reperfusion brachial artery<br /><br>3.Blood flow / oximetry after applying capsaicin-based cream<br /><br>4.Blood flow/ oximetry after applying brimonidine<br>