Expressive Writing as a Therapeutic Intervention in Male Infertility
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 56
- 试验地点
- 2
- 主要终点
- Scores on rating scale for perceived stress in infertility
研究概览
简要总结
The purpose of this study is to determine whether expressive writing can be effective in improving the well-being and sperm quality in patients with male infertility.
详细描述
Expressive writing is a therapeutic intervention designed by the psychologist James W. Pennebaker. Individuals write on three days for about 20 minutes about particularly stressful experiences in their life. Several studies showed that expressive writing can have beneficial effects on the frequency of health care utilization and well-being. Particularly in patients with rheumatism, kidney cancer and posttraumatic stress disorder expressive writing showed an positive effect on subjective well-being. Furthermore, in several studies expressive writing showed a positive effect on immune parameters.
As many studies suggest an important negative effect of stress on well-being and sperm parameters in male infertility, we want to investigate the effect of expressive writing in male infertility.The expressive writing condition is compared to a non emotional writing condition, in which individuals write about mainly non emotional topics such as time management. In this randomized-controlled trial subjects were allocated sequentially by block wise randomization (block size of 4). For randomization a computer generated random list was used. The allocation was concealed in a series of numbered sealed envelopes. The envelope was opened immediately before the first writing session.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 55 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Male infertile patients with a pathological spermiogram according to WHO criteria
排除标准
- •Drugs affecting sperm quality
- •Patients with chromosomal anomalies affecting sperm quality (e.g. Klinefelter- Syndrome)
- •Severe Psychiatric disorder defined as psychotic disorder (schizophrenia, bipolar disorder) or substance-related disorder
- •Patients currently in psychotherapeutic or psychiatric therapy
结局指标
主要结局
Scores on rating scale for perceived stress in infertility
时间窗: 3 months
次要结局
- Sperm parameters(3-12 months)
- Scores on rating scale for personality dimensions(3 months)
- Score on rating scale for coping(3 months)
