The influence of supplementary regional infiltration anesthesia with ropivacaine on postoperative pain, nausea and vomiting in patients undergoing mamma surgery under general anesthesia
Completed
- Conditions
- nausea and vomitingpain100062911000623210006295
- Registration Number
- NL-OMON35556
- Lead Sponsor
- Reinier de Graaf Groep
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
women
one-sided breast conserving surgery with or without sentinel node biopsy
age 18-80 yr
Exclusion Criteria
known allergy to amide type local anesthetics
severe liver failure
weight >120 kg
double-sided breast surgery
infections in the infiltration region
breast conserving surgery combined with plastic surgery
pregnancy/lactation
use of opiates
use of anti-emetics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>postoperative vomiting in the first 24 hours</p><br>
- Secondary Outcome Measures
Name Time Method <p>Postoperative nausea 4,8 and 24 hours after start of surgery (VAS score 0-10)<br /><br>Postoperative pain 4,8 and 24 hours after start of surgery (VAS score 0-10)<br /><br>Need for postoperative opiates (frequency and total dose in first 24 hours)<br /><br>Need for anti-emetics (frequency and total dose in first 24 hours)</p><br>