Effects of Time of Day and Nut Intake on Cognitive Performance: a Crossover Trial in Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- N-back task - accuracy
研究概览
简要总结
This is a 2 x 2-factor crossover design study to investigate the effects of time of day and nuts on post-meal cognitive performance.
详细描述
In this trial, eligible participants will receive isocaloric meals with or without nuts at lunchtime and dinner time. Cognitive performance will be performed before and 90 min after the meals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Non-shift workers
- •18-55 years
- •BMI between 18.5 and 27 kg/m2,
- •Non-smokers
- •Without chronic illnesses
排除标准
- •Allergy to nuts
- •BMI<18.5 or >27 kg/m2
- •Presence of dementia or psychiatric disease (depression, Parkinson's disease, schizophrenia)
- •Presence of diabetes, serious health conditions that may affect participation e.g. liver or thyroid dysfunction, recent major surgery, cardiovascular disease
- •Presence of any sleep disorders
- •Taking anti-diabetic or lipid-lowering medication
- •Do not speak English
- •Pregnant or planning on becoming pregnant
- •Breastfeeding
研究组 & 干预措施
Lunch nut-free meal
Participants will receive an isocaloric meal without nuts at lunchtime.
干预措施: Nut-free meal (Other)
Lunch nut meal
Participants will receive an isocaloric meal with nuts at lunchtime.
干预措施: Nuts (Other)
Dinner nut-free meal
Participants will receive an isocaloric meal without nuts at dinner.
干预措施: Nut-free meal (Other)
Dinner nut meal
Participants will receive an isocaloric meal with nuts at dinner.
干预措施: Nuts (Other)
结局指标
主要结局
N-back task - accuracy
时间窗: before meal x 90 min post-meal
Difference in the total accuracy
N-back task - reaction time
时间窗: before meal x 90 min post-meal
Difference in the reaction time for correct matched responses
Stroop test - incongruent
时间窗: before meal x 90 min post-meal
Difference in the reaction time for incongruent
Stroop test - interference
时间窗: before meal x 90 min post-meal
Difference in stroop interference (incongruent - congruent response time)
N-back task - matched responses
时间窗: before meal x 90 min post-meal
Difference in the % matched responses
N-back task - false alarm
时间窗: before meal x 90 min post-meal
Difference in the % false alarm
Stroop test - congruent
时间窗: before meal x 90 min post-meal
Difference in the reaction time for congruent
次要结局
- Multitasking - mixed blocks(before meal x 90 min post-meal)
- Satiety - satisfaction(Satisfaction will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins).)
- Satiety - hunger(Hunger will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins).)
- Satiety - eating capacity(Eating capacity will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins).)
- Multitasking - pure blocks(before meal x 90 min post-meal)
- Satiety index(Satiety index will be assessed before the meal and 4 times after the meal (15, 30, 60 and 90 mins).)
- Satiety - fullness(Fullness will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins).)
- Multitasking - mixing cost(before meal x 90 min post-meal)
研究者
Barbara R. Cardoso
Senior Lecturer
Monash University