An association between central sensitization and autonomic nervous system and an effect of aeobic exercise for patietns with knee and hip osteoarthritis
Not Applicable
Recruiting
- Conditions
- knee and hip osteoarthritis
- Registration Number
- JPRN-UMIN000048356
- Lead Sponsor
- International University of Health and Welfare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
The exclusion criteria are; (1) disabilities of cardiopulmonary vascular, central nervous and autonomic nervous system, (2) facial, chest and abdominal pain (3) cancer pain (4) patients who took exercise or physical therapy within three months (5) patients who is difficult to communicate and to answer questionnaire (6) patients who take fallowing medications; beta- blocker, antidepressant and anticonvulsant
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Conditioned pain modulation as a measure of central sensitization is a primary outcome of this study. Measurements will be performed before and after interventions.
- Secondary Outcome Measures
Name Time Method umerical analog scale of knee pain (intensity of knee pain) Heart rate variability (autonomic nervous activities) Heart rate recovery when aerobic exercise (autonomic nervous activities) Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC, disability) PainDETECT (neuropathic pain) Pain Catastrophizing Scale (pain catastrophizing) International Physical Activity Questionnaire (physical activity) Hospital Anxiety and Depression Scale (anxiety and depression) Pittsburgh Sleep Quality Index (sleep quality) Checklist for Individual Strength (fatigue) Basic characteristics (age, sex, diagnosis and level of OA, history of medicine, marital status, educational status, height, weight, body mass index, X-ray, medication, blood and urine sampling) Measurements will be performed before and after interventions.