Evaluating the effect of vitex agnus castus on treatment of premenstrual syndrome
Not Applicable
- Conditions
- Premenstrual syndrome.Premenstrual tension syndrome
- Registration Number
- IRCT201101035541N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 116
Inclusion Criteria
1- Age 18 and above
2- Single
3- Regular menstruation (interval: 24-35 days, duration: 2-8 days) in last year
4- Contemporary diagnosis of pms based on DSM-IV
5- Confirmed diagnosis of pms based on two screening cycles
Exclusion criteria:
1- Diagnosed physical or mental diseases
2- Using hormonal drugs, agonist or antagonist of dopamine ,or vitamins
3- Using antidepressant or herbal drugs
4- Participation in other same trials
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total symptoms of premenstrual syndrome. Timepoint: before treatment (two screening cycles)and after treatment (two treatment cycles). Method of measurement: Daily Symptoms Rating(DSR)contain 18 symptoms of premenstrual syndrome (10 psychological and 8 physical symptoms).;Psychological symptoms of premenstrual syndrome. Timepoint: before treatment (two screening cycles)and after treatment (two treatment cycles). Method of measurement: Daily Symptom Rating (DSR) (contain 10 psychological symptoms).;Physical symptoms of premenstrual syndrome. Timepoint: before treatment (two screening cycles)and after treatment (two treatment cycles). Method of measurement: Daily Symptom Rating (DSR) (contain 8 physical symptoms).
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: in two treatment cycles. Method of measurement: through check list of side effects.