Clinical and Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births

Not Applicable

Completed

• Conditions: Oral Findings in Children of Multiple and Single Births; Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
• Interventions: Other: The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births

• Registration Number: NCT04697017
• Lead Sponsor: Suleyman Demirel University

Brief Summary

Clinical and radiographic evaluation of oral findings in children of multiple and single births

Detailed Description

In this study, the study groups comprised MZ and DZ twin pairs, triplets and singletons between the ages of 2 and 17 who attended the Department of Pediatric Dentistry at Suleyman Demirel University between January 2018 and September 2020. Twins and triplets who had developmental anomalies such as cleft lip and palate, premature tooth loss, systemic diseases or syndromes that could influence oral health or had already undergone or were undergoing orthodontic therapy, as well as those whose family did not give consent, were excluded from the study.

All children were assessed by the same experienced pedodontist (E.O.) to avoid interexaminer variability. The oral examination was performed using sterile mouth mirror and probe. The prevalence of dental caries was recorded using dmft index (decayed, missing and filled teeth) in primary dentition and DMFT index (Decayed, Missing and Filled teeth) in permanent dentition. When evaluating patients over 6 years old, the missing tooth component was not included in the primary dft scores.

Oral hygiene practices, such as tooth brushing frequency and the children's past or present oral habits (digit sucking, nail biting, tongue thrust, bruxism, lip biting, pencil biting, cheek biting and mouth breathing), were also recorded.

The primary molar relationships were evaluated as flush terminal plane and mesial and distal step. The permanent molar relationships were recorded as Class I, Class II (Division 1 and 2) and Class III. Occlusal traits such as increased overjet, deep bite, open bite and anterior and posterior crossbite were recorded as present (1) or absent (0) with the help of a dental probe

Study Timeline

• Study Start: 2018-01-10
• Primary Completion: 2020-09-10
• Study First Submitted: 2021-01-02
• Study First Submitted QC: 2021-01-04
• Study First Posted: 2021-01-06
• Study Completion: 2021-09-10
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-04
• Last Update Posted: 2022-07-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 690

Inclusion Criteria

• Twins, triplets and singletons who had not

  • developmental anomalies such as cleft lip and palate
  • premature tooth loss
  • systemic diseases or syndromes that could influence oral health
  • already undergone or were undergoing orthodontic therapy

Exclusion Criteria

• Twins, triplets and singletons who had

  • developmental anomalies such as cleft lip and palate
  • premature tooth loss
  • systemic diseases or syndromes that could influence oral health
  • already undergone or were undergoing orthodontic therapy
  • those whose family did not give consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Singletons	The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births	Singletons who had developmental anomalies such as cleft lip and palate, premature tooth loss, systemic diseases or syndromes that could influence oral health or had already undergone or were undergoing orthodontic therapy, as well as those whose family did not give consent, were excluded from the study.
Multiple births (twins and triplets)	The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births	Twins and triplets who had developmental anomalies such as cleft lip and palate, premature tooth loss, systemic diseases or syndromes that could influence oral health or had already undergone or were undergoing orthodontic therapy, as well as those whose family did not give consent, were excluded from the study

Primary Outcome Measures

Name	Time	Method
Evaluation of molar relationship	Baseline	The primary molar relationships were evaluated as flush terminal plane and mesial and distal step. The permanent molar relationships were recorded as Class I, Class II (Division 1 and 2) and Class III
Clinical examination of dental caries	Baseline	The prevalence of dental caries was recorded using dmft index (decayed, missing and filled teeth) in primary dentition and DMFT index (Decayed, Missing and Filled teeth) in permanent dentition. When evaluating patients over 6 years old, the missing tooth component was not included in the primary dft scores.
Number of participants with oral habits	Baseline	the children's past or present oral habits (digit sucking, nail biting, tongue thrust, bruxism, lip biting, pencil biting, cheek biting and mouth breathing) were recorded.

Trial Locations

Locations (2)

Suleyman Demirel University Faculty of Dentistry Pediatric Dentistry Department; 🇹🇷 Isparta, Turkey

Esra; 🇹🇷 Isparta, Turkey