Genes and Gene Polymorphisms Associated with Infertility: Utilization of DNA Characteristics to Better Understand Reproductive Competence
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Infertility
- Sponsor
- Reproductive Medicine Associates of New Jersey
- Enrollment
- 5000
- Locations
- 1
- Primary Endpoint
- Number of retrieved oocytes
- Status
- Enrolling By Invitation
- Last Updated
- last year
Overview
Brief Summary
The purpose of this this study is to use DNA screening strategies to identify genes and localize genomic regions that are differentially expressed in patients with infertility to further understand the genetic basis for reproductive competence.
Detailed Description
Experimental strategies seek to discover small variants in DNA sequences, which are associated with certain infertility parameters. The alleles being analyzed in in vitro fertilization (IVF) population are sought to be associated with functional differences in the expression of the gene product that are then mechanistically linked to infertility.
Investigators
Eligibility Criteria
Inclusion Criteria
- •all patients undergoing fertility care
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Number of retrieved oocytes
Time Frame: 1 month
Secondary Outcomes
- Fertilization rate(1 month)
- Pregnancy rates(1 year)
- Number of available embryos(1 month)