Assessment the effect of Ca-Vitamin D and metformin on PCOS
Phase 2
Completed
- Conditions
- Condition 1: Polycystic ovarian syndrome. Condition 2: Female infertility associated with anovulation.Polycystic ovarian syndromeFemale infertility associated with anovulation
- Registration Number
- IRCT201009131760N9
- Lead Sponsor
- Vice Chancellor for Research and Technology, Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 75
Inclusion Criteria
1. Reproductive age range 18 to 35 years;
2. According to the Rotterdam criteria, the presences of two of the three following characteristics were required for inclusion in the study:
A. oligomenorrhea/amenorrhea;
B. chemical or clinical findings of hyperandrogenism;
C. polycystic ovaries on transvaginal sonography.
Exclusion criteria:
Patients with systemic diseases such as Cushing's syndrome, hyperparathyroidism or hyperprolactinemia, androgen secreting tumors, history of abdominal/pelvic surgery, coexisting male factor infertility, or abnormal hysterosalpingography were excluded from the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Calcium and vitamin D. Timepoint: After three months. Method of measurement: Laboratory.;Regulate menstruation. Timepoint: After three months. Method of measurement: 35-21 day intervals with standard.;Follicular growth. Timepoint: After three months. Method of measurement: Ultrasound.
- Secondary Outcome Measures
Name Time Method Pregnancy rate. Timepoint: After three months. Method of measurement: Ultrasound.