Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular Hypertension
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- Intaocular Pressure (IOP) Mean Change After 6 Weeks of Treatment
研究概览
简要总结
To compare the efficacy and safety in patients treated with travoprost versus dorzolamide/timolol maleate combination in patients with open-angle glaucoma or ocular hypertension
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with open-angle glaucoma or ocular hypertension
排除标准
- 未提供
研究组 & 干预措施
Travatan
Travatan: 6 weeks treatment with Travatan (travoprost 40 mg/ml eye drops, solution) once daily at 08:00 and placebo (timolol vehicle) once daily at 20:00 in the affected eye(s)
干预措施: Travatan (Drug)
Travatan
Travatan: 6 weeks treatment with Travatan (travoprost 40 mg/ml eye drops, solution) once daily at 08:00 and placebo (timolol vehicle) once daily at 20:00 in the affected eye(s)
干预措施: Placebo (Timolol Vehicle) (Drug)
Cosopt
treatment period of 6 weeks with Cosopt (dorzolamide 20 mg/ml and timolol maleate 5 mg/ml eye drops, solution) twice daily at 08:00 and 20:00 in the affected eye(s)
干预措施: Cosopt (Drug)
结局指标
主要结局
Intaocular Pressure (IOP) Mean Change After 6 Weeks of Treatment
时间窗: At week 0 and week 6
IOP measured at week 6 minus IOP measured at baseline
次要结局
未报告次要终点