The effect of combination of palonosetron and aprepitant for the prevention of postoperative nausea and vomiting in women patients using intravenous patient-controlled analgesia: combination of palonosetron and aprepitant vs palonosetron alone.
Not Applicable
Completed
- Conditions
- Not Applicable
- Registration Number
- KCT0002433
- Lead Sponsor
- Soon Chun Hyang University Hospital Seoul
- Brief Summary
.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
Healthy adult woman who is undergoing elective surgery under general anesthesia, and received intravenous patient-controlled analgesia using fentanyl for postoperative pain control
Exclusion Criteria
The patients with respiratory, cardiovascular, gastrointestinal, cerebral, renal, or hepatic disease.
The patients who experienced nausea and vomiting within 24 hours before surgery.
The patients who received antiemetics or steroids within 24 hours before surgery.
pregnant woman,
severe obese
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of nausea and vomiting during the 24 hours after operation.
- Secondary Outcome Measures
Name Time Method ausea severity, rescue antiemetics use, patients' satisfaction and adverse effects during 24 hours after operation