A Cross sectional Study of Fecal Microbiome among Japanese Children with Autistic Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Their Siblings and Typically Developing Childre
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactive Disorder
- Registration Number
- JPRN-UMIN000033163
- Lead Sponsor
- Keio University School of Medicine Neuropsychiatry dpt
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 160
Not provided
<In cases of ASD, ADHD children> Having other mental disorders, organic brain abnormalities (epilepsy, schizophrenia, obsessive-compulsive disorder, etc.) Having serious systemic physical disorders (thyroid dysfunction, immune diseases, etc.) Underwent surgery due to serious gastrointestinal disorder or in treatment of severe gastrointestinal disorders(gastrointestinal cancer, congenital bowel obstruction, Hirschsprung disease etc.) Received antibiotics within 3 months Collection of fecal samples can not be performed for any reason (such as mental symptoms can be worsened due to stress, etc.) Psychological symptoms may worsen due to mental and physical burden caused by interview evaluation conducted in this research Other reasons in which researchers considered to be inappropriate <In cases of their siblings> Having serious systemic physical disorders (thyroid dysfunction, immune diseases, etc.) Having undergone surgery due to serious gastrointestinal disorder or in treatment of severe gastrointestinal disorders(gastrointestinal cancer, congenital bowel obstruction, Hirschsprung disease etc.) Received antibiotics within 3 months Collection of fecal samples can not be performed for some reason Large burden caused by interview evaluation conducted in this research Other reasons in which researchers considered to be inappropriate <In cases of healthy participants> Family history of mental illness within the second degree, Having serious systemic physical disorders (thyroid dysfunction, immune diseases, etc.) Having undergone surgery due to serious gastrointestinal disorder or in treatment of severe gastrointestinal disorders(gastrointestinal cancer, congenital bowel obstruction, Hirschsprung disease etc.) Received antibiotics within 3 months Collection of fecal samples can not be performed for some reason Large burden caused by interview evaluation conducted in this research Other reasons in which researchers considered to be inappropriate
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method