Relation Between Substance Use and Pain, in Patients Suffering or Surviving From Cancer and Followed in France
- Conditions
- CancerPainSubstance Use
- Interventions
- Behavioral: Questionnaire (patient reported outcome)
- Registration Number
- NCT05684939
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Brief Summary
Pain is one of the most prevalent symptoms during and after cancer. Pain can be the consequence of several situations (disease progression, surgery, and anticancer drugs). However, pain can frequently be associated with a substance use disorder (alcohol, tobacco, drugs, and illicit products such as cannabis). The relationship between substance use and pain is known to be complex and interdependent, i.e. pain can reinforce substance use and substance use can promote pain. However, few data in the literature are available on the use of psychoactive substances in relation to pain in the context of cancer (cancer patients and cancer survivors). Moreover, the scientific literature agrees on the fact that these elements are little studied and underestimated in the clinic.
The investigators hypothesize that, in cancer patients or cancer survivors, the prevalence of the use of psychoactive substances would be higher in the presence of pain, and would be associated with its intensity and its impact on the quality Health-Related Living (HRQoL).
The main objective of this study will be to compare, in an adult population of patients suffering from cancer or having had cancer, the prevalence of the consumption of psychoactive substances in painful patients compared to non-painful patients.
- Detailed Description
Patients will answer to an online questionnaire thanks to associations of cancer patients and social networks, in order to explore their substance use and pain status.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2010
- Adult patient, male or female, declaring himself as suffering or having suffered from cancer and recruited as such via appropriate communication systems (patient associations, etc.)
- Difficulty to understand French language
- Residence outside France (will be verified by the information from the department at the start of the questionnaire)
- Patient close relative
- Protected adults
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description cancer patients and cancer survivors Questionnaire (patient reported outcome) answer to an online questionnaire
- Primary Outcome Measures
Name Time Method substance use day 1 Legal: alcohol, tobacco, electronic cigarette, psychotropic drugs (benzodiazepines, z-drugs, and opioids), CBD, and other susbtances Illegal: cannabis, and other drugs
At least once in the past year, at least once in the past month, at least once in the past week, or at least once a day
- Secondary Outcome Measures
Name Time Method Neuropathic pain day 1 DN4 interview questionnaire
Chemotherapy-induced peripheral neuropathy day 1 QLQ-CIPN20 questionnaire
Sociodemographic characteristics of patient day 1 age, sex, height, weight, body mass index, area of residence (urban or rural), socio-professional status (INSEE), and department
Pain severity day 1 Brief pain inventory
Intercurrent pathologies day 1 open question
Oncological characteristic day 1 type of cancer, date of cancer diagnosis, and type of treatment (received and/or ongoing)
Anxiety and depression day 1 HADS questionnaire
Analgesic use day 1 Ongoing analgesic drugs
Material and social deprivation day 1 EPICES questionnaire
Health-related quality of life and symptoms day 1 QLQ-C30 questionnaire
Trial Locations
- Locations (1)
CHU Clermont-Ferrand
🇫🇷Clermont-Ferrand, France