A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health

Completed

• Conditions: Gingivitis; Dental Plaque
• Interventions: Device: Oscillating-rotating electric toothbrush; Device: Manual toothbrush; Device: Sonic electric toothbrush

• Registration Number: NCT05594004
• Lead Sponsor: Procter and Gamble

Brief Summary

The aim of this analysis was to compare gingivitis- and plaque-reduction efficacy from randomized controlled trials (RCTs) up to six months long evaluating oscillating-rotating, sonic, and manual toothbrushes

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-01
• Primary Completion: 2022-07-29
• Study Completion: 2022-07-29
• Status Verified: 2022-10
• Study First Submitted: 2022-10-21
• Study First Submitted QC: 2022-10-21
• Last Update Submitted: 2022-10-21
• Study First Posted: 2022-10-26
• Last Update Posted: 2022-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2929

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Oscillating-Rotating electric toothbrush	Oscillating-rotating electric toothbrush	Twice daily brushing
Manual toothbrush	Manual toothbrush	Twice daily brushing
Sonic electric toothbrush	Sonic electric toothbrush	Twice daily brushing

Primary Outcome Measures

Name	Time	Method
Dental Plaque Scores	Up to 6 months (26 weeks)	Change from baseline as measured by mean plaque score reduction from baseline (via Turesky's Modification of Quigley-Hein index, or Rustogi Modified Navy Plaque Index).
Number of Bleeding Sites	Up to 6 months (26 weeks)	Change from baseline as measured on number of bleeding sites ( via gingival bleeding index, Loe Silness index, Gingival Bleeding Index (GBI), Papillary bleeding index or Mazza gingival index).

Trial Locations

Locations (1)

Multiple Study Locations; 🇺🇸 Cincinnati, Ohio, United States