A RANDOMIZED STUDY TO COMPARE THE EFFECT OF NEBULIZED ROPIVACAINE AND NEBULIZED ROPIVACAINE WITH DEXMEDETOMIDINE ON ATTENUATING HEMODYNAMIC RESPONSE TO INTUBATION IN PATIENTS UNDERGOING SURGERY UNDER GENERAL ANAESTHESIA
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- .To access and compare they hemodynamic changes HR , SBP, DBP,MAP, Spo2 and ETco2 in both the groups
研究概览
简要总结
THIS STUDY IS TO COMAPRE THEY EFFECT OF NEBULIZED ROPIVACAINE AND NEBULIZED ROPIVACAINE WITH DEXMEDETOMIDINE ON THE HEMODYNAMICE RESPONSE TO INTUBATION IN PATIENTS UNDERGOING SURGERY UNDER GENERAL ANAESTHESIA. PREOPERATIVE VITALS ARE MOINTORED AND BEFORE INTUBATION PATIENTS IS NEBULIZED WITH ONE OF THEY GROPUS AND AFTER NEBULIZATION THEY VITALS ARE MONITORED AND THEY ARE VITALS ARE MOINTORED THROUGH OUT THEY PROCEDURE AT DIFFERENT TIME INTERVAL AND AFTER EXTUBATION PATIENTS IS ACCESED FOR SORE THROAT AND COUGH RESPOSNE . ALL THIS DATA WOULD BE ENTRED IN EXCEL SHEET AND FINAL RESULT WOULD BE CONCULUDED.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Double
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient giving consent for study
- •Weight 40-70 kg
- •ASA grade 1 & 2
- •Patients undergoing surgery under general anaesthesia
- •All lab investigations within normal range.
排除标准
- •Patient with a history of sore throat or upper respiratory tract infection
- •Hemodynamically unstable patients
- •Emergency patients
- •Patients with a history of allergy to local anesthetics
- •Patents with a history of allergy to dexmedetomidine
- •Patients with a history of cardiac, liver, or renal disorders.
- •Patient with a difficult airway where the anticipated duration of laryngoscopy exceeded 15 seconds.
- •ASA 3 and 4.
结局指标
主要结局
.To access and compare they hemodynamic changes HR , SBP, DBP,MAP, Spo2 and ETco2 in both the groups
时间窗: Before Nebulization ,After Nebulization, Before Intubation ,After Intubation, 5 minute after intubation ,at skin closure ,after extubation, 5 minutes after extubation
次要结局
- 1. To compare the cough response at extubation in both the groups.(2. The incidence rate of postoperative sore throat. In both the groups.)
研究者
Ashu Agarwal
Jhalawar medical college Jhalawar