Norwegian COgnitive Impairment After STroke (NorCOAST) Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 816
- 试验地点
- 1
- 主要终点
- Score on the Montreal cognitive assessment (MOCA)
研究概览
简要总结
A prospective observational multicenter study aiming to describe incidence, and identify predictors for development of poststroke dementia (PSD) and mild cognitive impairment (MCI) after stroke
详细描述
About 15000 Norwegians suffer a stroke every year and 2/3 will be more or less disabled. In addition to motor impairments and comorbidities, disability after stroke is often related to post stroke dementia (PSD) or mild neurocognitive disorder (NCD). However, these problems are hardly addressed in stroke or dementia research and frequently ignored in clinical practise. In the Nor-COAST study an interdisciplinary research group will collaborate to establish a research platform across all Norwegian Health Authorities. The overall aim of the study is to improve competence on PSD and NCD in order to improve individual health outcomes following a stroke. The specific objectives are to determine the incidence of PSD and NCD and the consequences on function and use of health care services and to enhance the early detection of PSD and NCD by identifying a set of risk factors, ranging from genetics to physical activity. The incidence and impact of PSD and NCD on function and use of health care services, medication and life-style changes are important when planning future health care services. Tools identifying patients at risk might improve diagnostic work up and together with knowledge on pathogenic aspects it will contribute to future treatment and prevention of PSD and NCD.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Stroke diagnosis according to the WHO criteria
排除标准
- •Not scandinavian speaking
结局指标
主要结局
Score on the Montreal cognitive assessment (MOCA)
时间窗: 18 months
Performance based test
次要结局
- Time spent in upright position(18 months)
- Brain Imaging(18 months)
- Selfreported habits concerning smoking, alcohol, diet and medication using standardised questionnaires(18 months)
- Score on Short Physical Performance Battery (sppb)(18 months)
- Score on the Montreal cognitive assessment (MOCA)(3 months)
