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Clinical Trials/NCT02074917
NCT02074917
Unknown
Not Applicable

Comparison of Dynamic Knee Stability and Functional Outcomes in Anatomical Single-bundle ACL at Anteromedial or Central Tunnel Position - Prospective, Randomized and Double-blind Clinical Trial in Athletes

University of Sao Paulo1 site in 1 country40 target enrollmentOctober 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Rupture of Anterior Cruciate Ligament
Sponsor
University of Sao Paulo
Enrollment
40
Locations
1
Primary Endpoint
Dynamic Stability with force platform
Last Updated
12 years ago

Overview

Brief Summary

This is a prospective, randomized and double-blind clinical trial about anatomical single-bundle anterior cruciate ligament (ACL) reconstruction.

One of the most common causes of ACL reconstruction failure is poor graft positioning. There is evidence that graft placement aligned with native insertion sites results in superior clinical outcomes. Current anatomic ACL reconstruction concepts highlight the importance of the native anatomy to restore physiological knee kinematics more accurately.

This study aims to investigate clinical outcomes and dynamic knee stability with force platform and other functional tests after ACL reconstruction in two different groups of tunnel position: anteromedial ACL footprint (AM) or central ACL footprint.

It was hypothesized that there would be clinical or dynamic stability differences between AM or Central tunnel groups in ACL reconstruction.

Detailed Description

Tunnel position will be recorded and confirmed with postoperative computer tomography.

Registry
clinicaltrials.gov
Start Date
October 2012
End Date
October 2015
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Arnaldo José Hernandez

Associate Professor, PhD, MSc, MD

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

  • Physical activity classified by Tegner scale ≥ 5
  • Absence of other associated ligament injuries in the operated knee
  • No ACL rerupture or previous ACL reconstruction in the same or other knee
  • Absence of untreated lesions of the opposite knee
  • No obvious change in the alignment of the mechanical axis that required surgical correction
  • Athletes of both gender with a minimum age of 18 years and maximum of 45 years
  • Signature of the consent term (IRB)
  • Not be pregnant.

Exclusion Criteria

  • Request to stop the study by patient at any time
  • Fracture not associated with the surgical procedure
  • Do not carry out the rehabilitation protocol as oriented by the Sports Medicine group.

Outcomes

Primary Outcomes

Dynamic Stability with force platform

Time Frame: 12 months

Evaluation of dynamic stability in stand position and leg movements with force platform

Secondary Outcomes

  • Isokinetic knee strength test - side to side difference(6, 12 months)
  • Change from baseline and between groups in Dynamic Stability with force platform(6 months)
  • Change from baseline and between groups in International Knee Documentation Committee form (IKDC)(6, 12 e 24 months)
  • Change from baseline and between groups in Lysholm knee scoring scale(6, 12, 24 months)
  • Change from baseline and between groups in Tegner activity score(6, 12, 24 months)
  • Single leg hop test for distance - side to side difference(6, 12 months)

Study Sites (1)

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