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Role of tranexamic acid in reducing blood loss in hip fracture surgeries

Not Applicable
Conditions
Health Condition 1: S721- Pertrochanteric fracture
Registration Number
CTRI/2019/10/021667
Lead Sponsor
Sri Sathya Sai Institute of Higher Medical Sciences Prasanthigram
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Evans types 1 and 2

2. Internal fixation by Dynamic Hip Screw

Exclusion Criteria

1.Fractures managed with cephalomedullary nails or other surgical modalities.

2.Use of antiplatelet agents or anticoagulants at the time of admission

3.History of cardiac disease or cerebrovascular diseases

4. Documented allergy to TXA

5.History of DVT or pulmonary embolus

6.Hepatic dysfunction

7.Renal dysfunction

8.Derangement of blood coagulation parameters

9.History of malignancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Hb fall on day 5 after accounting for intraoperative and post-operative transfusionTimepoint: Hb fall on day 5 after accounting for intraoperative and post-operative transfusion
Secondary Outcome Measures
NameTimeMethod
Any complicationsTimepoint: 6 weeks from surgery;No. of packed cells transfused postoperativelyTimepoint: 6 weeks;Total, visible and hidden blood lossesTimepoint: 5th postoeprative day
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