Randomised Trial Comparing the Efficacy of Ocular Lubricant (Lacrilube) and Polyacrylamide Hydrogel Dressing (Geliperm) for the Prevention of Exposure Keratopathy in the Critically Ill
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Keratitis
- Sponsor
- Barts & The London NHS Trust
- Enrollment
- 40
- Primary Endpoint
- Development of clinically significant corneal exposure
- Status
- Completed
- Last Updated
- 18 years ago
Overview
Brief Summary
Corneal damage in critically ill patients is common. There are currently two popular methods of treatment in the UK; hydrogel dressings and lubricating ointment. We propose to randomise patients to have a different treatment for each eye and see which one is more effective.
Detailed Description
Microbial keratitis, particularly pseudomonas-related, has been widely reported amongst Intensive therapy unit (ITU) patients and the need for effective eye care in ITU has been recognised for some time. We compare two popular methods of eye care; a hydrogel dressing and lacrilube ointment. Each recruited patient had each eye randomised to different treatments. Daily ophthalmology ward rounds were undertaken to identify any corneal exposure keratopathy. Patients were removed from the trial if one eye developed significant exposure needing treatment.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients admitted to Intensive care and expected to stay for more than 2 days
Exclusion Criteria
- •Primary orbital injury
Outcomes
Primary Outcomes
Development of clinically significant corneal exposure
Time Frame: throughout length of admission to ITU