Deep Parasternal Intercostal Plane Block

Not Applicable

Recruiting

• Conditions: Nerve Block

• Registration Number: NCT06895876
• Lead Sponsor: Institute Arnault Tzanck, France

Brief Summary

Cardiac surgery is a source of severe post operative pain witch can cause major respiratory complications due to non optimal post operative rehabilitation.

Multimodal analgesia provides acceptable pain control , but does not seem sufficient during coughing or mobilization. The use of morphine also exposes patients to side effects (nausea, vomiting, pruritus, respiratory depression, chronic pain, ileus). Bleeding and hemodynamic risks of peridural and spinal aneshesia limits their use.

The postoperative efficacy of deep parasternal intercostal plane block has not yet been evaluated sufficiently. The aim of this study is to evaluate the efficacity of TTMPB on the quality of postoperative recovery after cardiac surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-03-04
• Study Start: 2022-08-10
• Primary Completion: 2025-02-12
• Status Verified: 2025-03
• Study First Submitted QC: 2025-03-25
• Last Update Submitted: 2025-03-25
• Study First Posted: 2025-03-26
• Last Update Posted: 2025-03-26
• Study Completion: 2025-06-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

• Patients requiring cardiac surgery with sternotomy

Exclusion Criteria

• Emergency procedure
• Procedures requiring lateral chest drainage
• Hemodynamic instability
• Severe kidney or liver failure
• BMI > 40
• Chronic pain
• Allergy to local anesthesics
• Pregnant woman
• Long term opioïds use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Quality of recovery 15 (QoR-15)	24 hours after surgery	QoR-15 score : 0 to 150. Addition of 15 items note between 0 to 10 150 = perfect post operative recovery possible 0 = worst post operative recovery possible

Secondary Outcome Measures

Name	Time	Method
Total morphine consumption at 24 hours	24 hours after surgery	Total morphine consumption, in milligrams, during the first 24 hours after surgery.

Trial Locations

Locations (1)

Institut Arnault Tzanck; 🇫🇷 Saint Laurent du Var, France