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Comparison of clopidogrel and prasugrel as prophylaxis for In-stent protrusion evaluated by optical coherence tomography in patients with ST-segment elevation myocardial infarctio

Phase 4
Conditions
ST-segment elevation myocardial infarction
Registration Number
JPRN-UMIN000017732
Lead Sponsor
Yokohama city university medical center Cardiovascular center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
All
Target Recruitment
50
Inclusion Criteria

Not provided

Exclusion Criteria

(1)Use of oral anticoagulants, ticlodipine, cilostazol and clopidogrel (2)Cardiopulmonary arrest or prolonged CPR (3)Cardiogenic shock (4)STEMI caused by coronary artery bypass graft disease or in-stent restenosis (5)Unsuitable for stent implantation (6)Severe chronic renal failure with serum creatinine >2mg/dL (7)Left main trunk disease (8) Serum hemoglobin level < 9g/dL or >18g/dL Platelet count < 50,000 /mm3 or > 500,000 /mm3 (9) Hematologic or malignant disorder with the life expectancy < 1 year (10)Major bleeding events within 7 days before enrollment (11) Severe liver dysfunction (hepatic cirrhosis or portal hypertension) (12)Drug allergy to aspirin, clopidogrel or prasugrel (13)Women of pregnant, childbearing potential or lactation (14)Participating in the other trial (phase 1-3) (15)Patients who are not allowed to participate in the trial by judgement of the treating physician

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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