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Clinical Trials/NCT05526573
NCT05526573
Recruiting
Not Applicable

Diagnostic Yeld of Ultrathin Bronchoscopy in Peripheral Pulmonary Lesions

Azienda Sanitaria-Universitaria Integrata di Udine3 sites in 1 country148 target enrollmentJuly 14, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Lung TB
Sponsor
Azienda Sanitaria-Universitaria Integrata di Udine
Enrollment
148
Locations
3
Primary Endpoint
Evaluate the overall diagnostic accuracy
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The use of an ultrathin bronchoscope (UB) has recently been introduced in the diagnosis of peripheral lung lesions. The use of the UB can be supported by navigation systems such as fluoroscopy, ultrasound guidance, electromagnetic navigation, or other technologies, which have complementary potential. Further navigation techniques are still under study. The use of ultrathin instrumentation has already been shown to significantly reduce procedural times compared to traditional instrumentation.

The purpose of the study is to prospectively evaluate the institutional experience of different third-level hospital centers with the use of a UB (MP190F; Olympus Medical Systems, Tokyo, Japan) for sampling peripheral lung lesions by means of transbronchial needle aspiration (TBNA) or transbronchial biopsy (TBB), performed after fluoroscopic navigation and simultaneous radial probe-endobronchial ultrasound (RP-EBUS) assessment.

Design: multicentric, observational study.

Registry
clinicaltrials.gov
Start Date
July 14, 2022
End Date
December 31, 2025
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Alberto Fantin

Principal Investigator

Azienda Sanitaria-Universitaria Integrata di Udine

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Evaluate the overall diagnostic accuracy

Time Frame: Within 12 months from the procedure

Sensitivity, specificity, positive predictive value, negative predictive value

Secondary Outcomes

  • Agreement between the definitive pathological result and the rapid on-site evaluation (R.O.S.E.)(Within 15 days from the procedure)
  • Evaluation of patient satisfaction at the end of the procedure (Likert scale in relation to the memory of the procedure and the willingness to repeat it in the future.)(Same day of the procedure)
  • Correlation between the type of anesthesia, the characteristics of the lesion, the procedural dynamics and diagnostic accuracy(Within 12 months from the procedure)
  • Correlation between the type of anesthesia, the characteristics of the lesion, the procedural dynamics and patient satisfaction(Same day of the procedure)

Study Sites (3)

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