Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease

Phase 4

Completed

• Conditions: Hemorrhoids
• Interventions: Drug: CDobi; Drug: Flavonoids

• Registration Number: NCT02782455
• Lead Sponsor: Services Hospital, Lahore

Brief Summary

Haemorrhoids are vascular cushions in the anal canal that help in the control of stool. When inflamed they become pathological and may present with protrusion and bleeding. A randomized, triple blind , controlled study will be conducted to compare the efficacy of calcium dobesilate against flavanoids in the management of early haemorrhoidal disease.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-03-10
• Study First Submitted QC: 2016-05-20
• Study First Posted: 2016-05-25
• Study Start: 2016-12-01
• Primary Completion: 2018-11-30
• Study Completion: 2018-11-30
• Status Verified: 2018-12
• Last Update Submitted: 2018-12-23
• Last Update Posted: 2018-12-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Grade I and Grade II hemorrhoids

Exclusion Criteria

• CLD
• colorectal/ anorectal Malignancy
• self medication
• local Quack Hakeem medication
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CDobi	CDobi	Calcium dobesylate is given in this group
Flavono	Flavonoids	Flavonoids are given in this group

Primary Outcome Measures

Name	Time	Method
Frequency of occurrence of rectal bleeding after usage of drug	1 weeks	After the patients will be given the two drugs they will be followed for the frequency of occurrence of rectal bleeding till two weeks

Secondary Outcome Measures

Name	Time	Method
regression of hemorrhoids	1 weeks	Patients will under gone per rectal examination and proctoscopy to look for grades of hemorrhoids whether its has decreased or increased.

Trial Locations

Locations (1)

Services Hospital Lahore; 🇵🇰 Lahore, Punjab, Pakistan