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Stroke Of Mindfulness: Investigating Physiological and Psychological Well-being

Not Applicable
Completed
Conditions
Depression
Stroke
Stress
Anxiety
Interventions
Behavioral: Mindfulness-Based Intervention
Behavioral: Waitlist - Mindfulness-Based Intervention
Registration Number
NCT03659409
Lead Sponsor
Singapore General Hospital
Brief Summary

This study evaluates the impact of mindfulness-based interventions on psycho-social and physiological well-being among stroke survivors and their family caregivers. This study will employ a treatment wait-list cross-over design, with half the participants randomized to receive the intervention first (treatment group), while the other half receives the interventions 2 months following the end of the treatment phase (wait-list group).

Detailed Description

Stroke survivors face many concerns, including the physical, psychological, cognitive and psychosocial consequences of stroke, as well as impaired function and quality of life. Also important for stroke survivors is the possibility of recurrence that may result in death and further disability. Survivors depend on their caregivers to provide assistance for daily living tasks, emotional support and taking on new roles and responsibilities with changing social dynamics, often causing long-term strain.

Mindfulness-based interventions (MBIs) are psychotherapeutic interventions which have been shown to improve psychological, physiological and psychosocial outcomes such as anxiety, depression, mental fatigue, blood pressure and overall quality of life. However, data is limited for stroke survivors and their caregivers, especially in Asians. This study will evaluate the impact of MBIs on the psychological well-being and perceived quality of life among stroke survivors and their family caregivers in Singapore.

This study employs a randomized treatment-waitlist crossover design with outcome measures administered before and after the intervention as well as at 3 months follow-up for the treatment group.

The intervention consists of 4 weekly 2-hour mindfulness sessions. Participants will be introduced, taught and guided in practice of mindfulness-based interventions that are focused on their (1) breath, (2) senses, (3) body and bodily movement, (4) feelings of empathy and compassion. Pre- and post-intervention questionnaires will be conducted to assess symptoms associated with depression, anxiety, stress and perceived quality of life. Blood pressure and heart rate variability recordings before and after intervention will also be noted.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Stroke Survivors
  • Family Caregivers
  • Able to speak and understand English Fluently
  • Comprehends and provides consent independently
Exclusion Criteria
  • Cognitively impaired individuals with a MMSE Score of less than 20, MoCA score of less than 23
  • Depression and Anxiety Stress Scale Scores, DASS, Depression >7, Anxiety >8, and Stress >13

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Mindfulness Based InterventionMindfulness-Based Intervention4 weekly 2-hour sessions. Participants will be introduced, taught and guided in practice of mindfulness-based interventions that are focused on their (1) breath, (2) senses, (3) body and bodily movements, (4) feelings of empathy and compassion.
Treatment Waitlist GroupWaitlist - Mindfulness-Based InterventionParticipants will receive no intervention, except for a baseline follow-up at the start and again at the end of the first phase. 2 months after the end of the first intervention phase, participants in this group will receive the same mindfulness-based intervention for 4 weeks.
Primary Outcome Measures
NameTimeMethod
Cohen Perceived Stress ScalePast 1 Month

A 10-item measure evaluating the perception of stress.

Centre for Epidemiologic Studies Depression Scale (CES-D)Past 1 Week

A 20-item measure for epidemiological research on depression.

Stroke Specific Quality of Life Scale (SS-QOL)Past 1 Month

A 49-item self-report questionnaire designed to measure the heath related quality of life specific to stroke survivors across 12 domains.

Stroke Impact Scale (SIS)1 week

A 64-item questionnaire that assesses across 8 domains

Short-Form-36 (SF-36)A range from the past 4 to 52 weeks

A 36-item self-report survey of health, including physical and mental health. Higher scaled scores reflect better quality of health.

Secondary Outcome Measures
NameTimeMethod
Zarit Burden InterviewPast 1 Month

A 22-item self-report questionnaire to measure for level of caregiver burden or stress.

Five Facet Mindfulness QuestionnairePast 1 Month

This 39-item instrument is based on a factor analytic study of five independently developed mindfulness questionnaires. The analysis yielded five factors that appear to represent elements of mindfulness as it is currently conceptualized. The five facets are observing, describing, acting with awareness, non-judging of inner experience, and non-reactivity to inner experience.

Big Five Personality InventoryPast 1 Month

44-item inventory that measures an individual on the Big Five Factors (dimensions) of personality (Goldberg, 1993). Each of the factors is then further divided into personality facets.

Trial Locations

Locations (1)

Singapore General Hospital

🇸🇬

Singapore, Singapore

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