Effect of oral and intravenous Tranexamic Acid for preventing postpartum hemorrhage after cesarean delivery
Not Applicable
Recruiting
- Conditions
- Hemorrhage after cesarean delivery.Maternal care for scar from previous cesarean deliveryO34.21
- Registration Number
- IRCT20151228025732N78
- Lead Sponsor
- Semnan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
Age between 18 and 40 years
Candidate for non-emergency cesarean section
A singleton pregnancy with a gestational age between 38 and 39 weeks that has been confirmed by ultrasound
Exclusion Criteria
Preeclampsia, premature birth, prolonged rupture of the water sac, multiple births
Visualization of fetal anomalies by ultrasound
Previous history of systemic diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure. Timepoint: Before the start of cesarean section and 2 hours after surgery. Method of measurement: Heart monitor device.;Postpartum bleeding volume. Timepoint: The difference in the weight of sheets, gauze and long gauze used during surgery and up to 2 hours after surgery. Method of measurement: Mahek brand digital scale (made in Iran with an accuracy of 0.1 gr).
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms of Tranexamic Acid inhibit plasminogen activation in postpartum hemorrhage prevention after cesarean delivery?
How does the efficacy of oral vs. intravenous Tranexamic Acid compare to oxytocin in reducing postpartum hemorrhage after C-sections?
Which biomarkers correlate with response to Tranexamic Acid in patients with uterine atony or previous cesarean scar-related hemorrhage?
What are the thromboembolic risks and management strategies for Tranexamic Acid use in IRCT20151228025732N78 trial participants?
Are there synergistic effects of combining Tranexamic Acid with hemostatic agents like carboprost for postpartum hemorrhage prevention?