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Clinical Trials/NCT04195672
NCT04195672
Completed
Not Applicable

Official Title Evaluation of the Value of Newborn Infant Parasympathetic Evaluation (NIPE) in Sedated/Ventilated Patients in Pediatric Intensive Care Unit

University Hospital, Lille1 site in 1 country32 target enrollmentNovember 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ventilator Lung; Newborn
Sponsor
University Hospital, Lille
Enrollment
32
Locations
1
Primary Endpoint
Newborn Infant Parasympathetic Evaluation
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The main objective is to assess correlation between Newborn Infant Parasympathetic Index values and external evaluation by Comfort Behaviour Scale during painful medical cares in sedated intubated children admitted in pediatric intensive care unit.

Detailed Description

The assessment of pain in patient hospitalized in intensive care remains a challenge, especially for patients which are unable to communicate their pain intensity. Self-reported scales are widely used for children's pain assessment but cannot be used in sedated or non-communicable patients. The gold standard for pain evaluation in sedated-ventilated patient in pediatric intensive care unit is the Comfort Behaviour Scale (CBS). However, this method remains subjective, depending on training and ability to use this clinical tool by the examiner. The Newborn Infant Parasympathetic Evaluation (NIPE) is a non-invasive system based on the analysis variability in high frequency (\> 0.15 Hz) which reflects the parasympathetic activity related to respiratory fluctuations of heart rate. With a numerical index ranging from 0 to 100, NIPE values, measured continuously, has been developed to evaluate the degree of pain intensity. In this study, the hypothese is the NIPE could be used as an indicator of pain in sedated/intubated children under 3 years-old hospitalized in Pediatric intensive care unit. This study did not change the procedure of care before or after and had no impact on care.

Registry
clinicaltrials.gov
Start Date
November 1, 2017
End Date
April 30, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Lille
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • All consecutive patient ≤ 3 year-old, mechanically ventilated

Exclusion Criteria

  • Withdraw life-support,
  • unstable condition preventing planned routine procedures of care,
  • conditions precluding the use of NIPE (cardiac transplant, absence of sinus cardiac rhythm, apnea or respiratory rate ≤ 25 /min, pacemaker and use of atropine and/or isoprenaline and conditions of days of availability for NIPE)

Outcomes

Primary Outcomes

Newborn Infant Parasympathetic Evaluation

Time Frame: Through the study completion (18 months)

Comparison between Newborn Infant Parasympathetic Evaluation values (0 to 100) and Comfort Behaviour Scale values (8 to 40) assessed by coefficient of correlation in patients upper than three years old

Comfort Behaviour Scale

Time Frame: Through the study completion (18 months)

Comparison between Newborn Infant Parasympathetic Evaluation values (0 to 100) and Comfort Behaviour Scale values (8 to 40) assessed by coefficient of correlation in patients upper than three years old

Secondary Outcomes

  • Newborn Infant Parasympathetic Evaluation(Through the study completion (18 months))

Study Sites (1)

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