Comparative clinical and radiographic evaluation of efficacy of demineralized bone matrix versus demineralized freeze dried bone allograft in treatment of infrabony defects: a randomized controlled clinical trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Plaque index (PI), Gingival index (GI), Probing pocket depth (PD), Relative attachment level (RAL)
研究概览
简要总结
The study will be done to evaluate clinical & radiographic efficacy of Demineralized Bone Matrix in comparison of that of Demineralized Freeze Dried Bone Allograft in treatment of infrabony defects. It will be a randomized controlled clinical trial. Total treatment sites will be 30 with chronic periodontitis. After 3-4 weeks of scaling, patients will be called for surgical procedure. After incision, reflection and degranulation; the infrabony defects will be filled with either Demineralized Bone Matrix or Demineralized Freeze Dried Bone Allograft according to the inclusion groups. The flaps will be sutured with 4 0 silk sutures. Plaque index, gingival index, pocket probing depth and clinical attachment level will be recorded preoperatively and postoperatively. Radiographs will be taken preoperatively and postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of both sexes having no systemic conditions that would contraindicate routine periodontal procedures.
- •Age More than or equal to 25 years of age, with no history of any periodontal surgery in the past 1 year.
- •The sites having radiographic evidence of angular bone loss More than or equal to 3 mm deep and probing depth of More than or equal to 5 mm.
排除标准
- •Participants who had received periodontal flap/regenerative therapy within the past 1 year.
- •Patients with deleterious oral habits such as smoking, tobacco chewing.
- •Pregnant and Lactating mothers.
- •Patients who were on antibiotic and nonsteroidal anti-inflammatory drugs within the past 1 year.
结局指标
主要结局
Plaque index (PI), Gingival index (GI), Probing pocket depth (PD), Relative attachment level (RAL)
时间窗: At baseline, 1 month and 6 months
次要结局
- Radiographic evaluation(Baseline)