The Mechanical Properties of Burned Muscles

Not Applicable

Completed

• Conditions: Viscoelastic Properties; Burns; Stiffness; Muscle Loss
• Interventions: Diagnostic Test: Myotonometric measurement

• Registration Number: NCT04654572
• Lead Sponsor: Hasan Kalyoncu University

Brief Summary

The investigate of mechanical properties of muscles in burned patients.

Detailed Description

The hypermetabolic response to severe burn is characterized by muscle protein catabolism. Current opinion states that the hypermetabolic state resolves soon after complete wound closure. Clinically, we have witnessed that burned patient appear to be hypermetabolic and catabolic long after full healing of their wounds. Our goal in this study was to determine muscle mechanical properties (tone, stiffness and elasticity) after burn.

Study Timeline

• Study Start: 2018-06-06
• Primary Completion: 2019-03-20
• Study Completion: 2020-08-20
• Study First Submitted: 2020-11-27
• Status Verified: 2020-12
• Study First Submitted QC: 2020-12-03
• Study First Posted: 2020-12-04
• Last Update Submitted: 2020-12-14
• Last Update Posted: 2020-12-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• burned patient
• major burn over %20 TBSA

Exclusion Criteria

• Amputation
• Dead
• Systemic disease and abuse

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
burned group	Myotonometric measurement	burned patients
control group	Myotonometric measurement	sedentary people

Primary Outcome Measures

Name	Time	Method
Stiffness	6 week	Myotonometric measurement was used to determine for muscle stiffness. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.
Tone	6 week	Myotonometric measurement was used to determine for muscle tone. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.
Elasticity	6 week	Myotonometric measurement was used to determine for muscle elasticity. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.

Trial Locations

Locations (1)

Hasan kalyoncu üniversity; 🇹🇷 Gaziantep, Turkey