A randomized controlled trial of airway pressure release ventilation and low tidal volume ventilation in pediatric acute respiratory distress syndrome

Phase 2

Recruiting

• Conditions: pediatric acute respiratory distress syndromeairway pressure release ventilation; pediatric acute respiratory distress syndrome; airway pressure release ventilation; low tidal volume ventilation; APRV; ARDS

• Registration Number: TCTR20170320002
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-20
• Study Completion: 2018-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

1.patients who diagnosed with moderate to severe acute respiratory distress syndrome by definition of The Pediatric Acute Lung Injury Consensus Conference Group (PALICC)
2.patients aged between 1 month - 15 years old
3.all patients were obtained informed consent from parents/ legal representative

Exclusion Criteria

1.congestive heart failure
2.air leak syndrome or preexisting cystic lung disease
3.terminal illness (life expectancy less than 3 months)
4.unstable hemodynamics

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
oxygenation 72 hours PaO2/FiO2

Secondary Outcome Measures

Name	Time	Method
all causes of mortality 28 days mortality rate,sedation 7 days total sedation requirement ,28 days - ventilator free day 28 days duration of ventilator free day within 28 days after onset,oxygen index 72 hours mean airway pressure x FiO2/PaO2