Radiotherapy Treatments for Neoplasms in the Head and Neck Region
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 4,050
- Locations
- 1
- Primary Endpoint
- Overall Survival
Study Overview
Brief Summary
The aim of this study is the evaluation of clinical and dosimetric aspects, tolerance, and effectiveness of radiotherapy treatments in the head and neck region.
Eligible patients undergoing radiotherapy for primary or secondary neoplasms localized in the head and neck anatomical region.
Detailed Description
Approximately 60% of patients with neoplasms receive radiotherapy as part of their oncological treatment.
Various primary tumors as well as metastases of various origins can be localized in the head and neck anatomical region. Patients with such neoplastic localizations will therefore receive radiotherapy treatment possibly associated with other systemic or surgical treatments.
Treatment choice is usually established following multidisciplinary discussions, based on disease characteristics and stage, concurrent pathologies and pharmacological treatments, patient preferences, and functional aspects.
The collection of data related to radiotherapy plays a crucial role in understanding various clinical aspects of the treatment itself. The availability of data from an increasing number of patients will allow the identification of clinical situations or technical parameters of radiotherapy correlated with treatment tolerance and effectiveness, aiming to identify the best treatment for these oncological pathologies.
This project aims to collect data related to radiotherapy treatments for primary or secondary neoplasms of the head and neck region for scientific dissemination with the goal of establishing the basis for evaluating achieved results over time, and deriving from these elements useful for guiding the most effective treatment strategies and appropriate operational protocols.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients treated with radiotherapy for curative, palliative, neo-adjuvant, and adjuvant purposes in the head and neck region include those with:
- •Primary bone tumors,
- •Primary soft tissue tumors,
- •Primary tumors of the cardio-circulatory system,
- •Primary tumors of the lymphatic system,
- •Primary tumors of the nervous system and skin,
- •Secondary metastases from various origins localized in that district.
- •Signed informed consent
Exclusion Criteria
- •Radiotherapy in districts other than the head and neck region
Outcomes
Primary Outcomes
Overall Survival
Time Frame: 5 years
Number of patients death
Disease free survival
Time Frame: 5 years
Number of oncological event (local recurrence, distant metastasis, other primary tumor)
Secondary Outcomes
No secondary outcomes reported