Comparative study on efficacy of Erandadi kwatha and symhasyadi kwatha in treatment of Gridhrasi (sciatica)

Phase 2/3

Not yet recruiting

• Conditions: Nerve root and plexus compressionsin diseases classified elsewhere. Ayurveda Condition: GRUDHRASI,

• Registration Number: CTRI/2025/05/087834
• Lead Sponsor: Shree saptashrungi Ayurved Mahavidyala and Hospital Kamal Nagar Hirawadi Panchawati Nashik

Brief Summary

Primary objectives - 1) To study the effect of Erandadi kwatha in Gridhrasi

2) To study the effect of Simhasyadi Kwatha in Gridhrasi.

3) To compare the effect of Erandadi kwatha with Simhasyadi Kwatha in management of Gridhrasi with special reference to sciatica

Study -  Comparative clinical study.

Group A - Erandadi kwatha

Group B - Simhasyadi Kwatha



Duration of treatment - 30 Days

Initial assessment on 1st day

Follow up on 15th and 30th day



Data Analysis - Data will be analysed  using appropriate statistical methods to compare the effectiveness of intervention on primary and secondary outcomes.



Ethical considerations - The study will be conducted in accordance with Ethical Guidelines and with infirmed consent from participants.

Conclusion - conclusion will be drawn on the basis of statistical analysis of data.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-05-28
• Study Start: 2025-09-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patient having positive straight leg raise test.

Exclusion Criteria

• 1. patient having lower limb paraplegia or hemiplegia.
• 2. pregnant and lactating women.
• 3. History of any vertibral/surgical/diagnostic intervention with reference to affected joints 4) gross disability in performing daily normal routine that is bedridden patient or confined to wheelchair 5) patient with known comorbidities such as gouty arthritis, rheumatoid arthritis or psoriatic arthritis, tubercular arthritis 6) patient with evidence of malignancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in signs and symptoms of gridhrasi	At base line 15th and 30th day

Secondary Outcome Measures

Name	Time	Method
Reduction in sign & symptoms of Gridhrasi with improvement in SLR test Grading	30th Day

Trial Locations

Locations (1)

Shree saptashrungi Ayurved Mahavidyala and Hospital; 🇮🇳 Nashik, MAHARASHTRA, India

Shree saptashrungi Ayurved Mahavidyala and Hospital

🇮🇳Nashik, MAHARASHTRA, India

Dr Vaishnavi kiranrao Sowale

Principal investigator

8999349832

Vaishnavi.sowale@gmail.com