Association of Intestinal Microbiota and the Onset of Perianal Abscess Based on 16S RDNA Amplicon Sequencing

Xi'an Hospital of Traditional Chinese Medicine1 site in 1 country100 target enrollmentJune 1, 2023

ConditionsPerianal Abscess

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Perianal Abscess
Sponsor: Xi'an Hospital of Traditional Chinese Medicine
Enrollment: 100
Locations: 1
Primary Endpoint: Observation group: the structure and changes of rectal flora before and after treatment
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this observational study is tolearn the association of gut microflora with the onset of perianal abscesses. The main questions it aims to answer are:

Question 1: To understand the structure of rectal microbial community composition and its relationship with pathogenic bacteria in patients with perianal abscess.

Question 2: Understand the structure of rectal microbial community composition in healthy people.

Participants will be collected with rectal secretions and stool specimens.In addition, patients with perianal abscess should also collect pus samples.

Registry

clinicaltrials.gov

Start Date

June 1, 2023

End Date

June 30, 2024

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Xi'an Hospital of Traditional Chinese Medicine

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Observation group: ① Age between 18-60 years, local resident of Xi'an; ② met the diagnostic criteria for perianal abscess and underwent surgical treatment in our hospital; ③ did not use antibiotics before treatment; ④ himself and his family members were willing to participate in this study and signed informed consent.
•Control group: ① Age between 18-60 years, permanent residents in Xi'an; ② had no serious chronic disease, no abnormality in physical examination in the last 1 week; ③ did not use drugs that may affect intestinal flora in the last one month; ④ himself and his family members are willing to participate in the study and sign the informed consent.