A study to assess the effect of coffee on the ability to perform simple physical and mental exercises in healthy individuals during the post-lunch period

Completed

Conditions: Healthy individual

Registration Number: CTRI/2019/02/017763

Lead Sponsor: Dr Suganthi S

Brief Summary: Psychomotor performance of the individual including attention span, concentration has been shown to be reduced during the post-lunch period. This post-lunch dip phenomenon has been seen even if the individuals has not consumed lunch and has been linked to 12-hour harmonic in 24-hour circadian rhythm. Caffeine tablets at 3 mg/kg, when added to decaffeinated coffee, was found to increase attention span and mood of the individual during this post-lunch period. However, the effect of regular coffee of caffeine at the dose of 100 mg on critical flicker fusion test, multiple choice reaction time and hand steadiness test has not been directly studied. Hence, the present study aims to evaluate the effect of regular and decaffeinated coffee on psychomotor performance (critical flicker fusion test, multiple choice reaction time and hand steadiness test) in healthy volunteers during the post-lunch period.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 16

Inclusion Criteria

1.Age 21-35 years 2.Willing to provide informed consent.

Exclusion Criteria

1.Current Smokers (Adult who have smoked at least 100 cigarettes in their lifetime and who currently smokes cigarettes) 2.H/o medication intake (especially, H/o drugs causing psychomotor impairment (anti-histamines, benzodiazepines), caffeine containing medicinal preparations, CYP1A2 inducers & inhibitors)) 3.H/o cough and cold for past 1 week 4.H/o caffeine use disorder (DSM V criteria) 5.H/o any other concurrent illness (hypertension, diabetes mellitus) 6.H/o heavy coffee drinking (consuming more than 4 cups of any type of coffee, caffeinated beverages every day) 7.H/o person who have never consumed caffeinated beverages or caffeine in any form 8.Pregnant and lactating females.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. difference in mean critical flicker fusion frequency between regular and decaffeinated group	1 hour post intervention
2. difference in average choice reaction time between regular and decaffeinated group	1 hour post intervention
3. difference in mean error count in hand steadiness test between regular and decaffeinated group	1 hour post intervention

Secondary Outcome Measures

Name	Time	Method
difference in blood pressure and heart rate between regular and decaffeinated group	1 hour post intervention

Trial Locations

Locations (1): Clinical Pharmacology laboratory
🇮🇳
Delhi, DELHI, India
Clinical Pharmacology laboratory
🇮🇳Delhi, DELHI, India
Dr Suganthi S
Principal investigator
9968859563
drsugiram@yahoo.in