Changes of total antioxidant capacity and total oxidant status of aqueous humor in different stages of diabetic retinopathy and non-diabetic patients.

Not Applicable

Completed

• Conditions: Diabetic Retinopathy; Eye - Diseases / disorders of the eye

• Registration Number: ACTRN12612000863831
• Lead Sponsor: lucanlar eye research and training hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-08-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

Inclusion criteria included diabetic patients who had diagnosis of senile cataracts. For non-diabetic patients inclusion criteria was presence of cataract.

Exclusion Criteria

Exclusion criteria included patients who had dense cataract which hinder retinopathy staging, previous ocular surgery, type 1 diabetes, history of glaucoma, retinal vein occlusion, uveitis, any other posterior segment pathologies.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1- Total antioxidant status and total oxidant satus of all aqueous humor samples measured.<br>Measurements of total antioxidant capacity and total oxidant status performed via new calorimetric method known as Erel method.[1-At january 2011, at the end of data collection, one month before end of study.]

Secondary Outcome Measures

Name	Time	Method
1-Measured oxidative and antioxidative stress markers compared with diabetic retinopathy levels.<br><br>Statistical analysis was done via SPSS Windows 15.0 program.<br>Basicly Sperman and Pearson correlation tests were used for analysis.[1-at one month after data collection]