PARAMEDIC 2: The Adrenaline Trial
- Conditions
- Out of hospital cardiac arrestCirculatory SystemCardiac arrest
- Registration Number
- ISRCTN73485024
- Lead Sponsor
- niversity of Warwick (UK)
- Brief Summary
1. 2016 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/27650864 2. 2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/30021076 3. 2020 case study results in https://www.ncbi.nlm.nih.gov/pubmed/31937351 (added 16/01/2020) 4. 2020 analysis in https://www.ncbi.nlm.nih.gov/pubmed/32002593 (added 03/02/2020) 5. 2019 results in https://pubmed.ncbi.nlm.nih.gov/31116964/ (added 02/09/2020) 6. 2020 cost-effectiveness results in https://pubmed.ncbi.nlm.nih.gov/32981529/ (added 30/09/2020) 7. 2021 results in https://pubmed.ncbi.nlm.nih.gov/33861194/ (added 19/04/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 8014
1. Cardiac arrest in out of hospital environment
2. Advanced life support initiated and/or continued by ambulance service clinician
1. Known or apparent pregnancy
2. Known or apparently aged under 16 years
3. Cardiac arrest secondary to anaphylaxis
4. Adrenaline given prior to arrival of ambulance service clinician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival to 30 days post cardiac arrest
- Secondary Outcome Measures
Name Time Method <br> 1. Survived event (sustained ROSC, with spontaneous circulation until admission and transfer of care to medical staff at the receiving hospital)<br> 2. Survival to hospital discharge (the point at which the patient is discharged from the hospital acute care unit regardless of neurological status, outcome or destination) 3, 6 and 12 months<br> 3. Neurological outcome at hospital discharge, 3 and 6 months<br> 5. Health related quality of life at 3 and 6 months<br> 6. Hospital length of stay<br> 7. Intensive care length of stay<br>