NCT01060969已完成不适用
Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 2
- 主要终点
- Results will be evaluated by using the Lake Louise AMS scoring system
研究概览
简要总结
To evaluate the additive value of tadalafil given together with Diamox (acetazolamide) in preventing acute mountain sickness in travelers to high altitude areas.
详细描述
A randomized controlled study comparing:
Tadalafil [20mg x1/day] and acetazolamide [125mg x2 day], versus Acetazolamide [125mg x2 day] alone, in trekkers to altitude > 3,000 m.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participant in trekking to high altitude
- •Agreement to sign the informed consent.
排除标准
- •No agreement to sign informed consent.
研究组 & 干预措施
Acetazolamide
Active Comparator
acetazolamide 125 mg BID
干预措施: Acetazolamide (Drug)
Acetazolamide and Tadalafil
Experimental
Intervention arm
干预措施: Tadalafil and acetazolamide (Drug)
结局指标
主要结局
Results will be evaluated by using the Lake Louise AMS scoring system
时间窗: one month after travel
次要结局
未报告次要终点
研究者
Prof. Eli Schwartz MD, DTMH
Head of the Center for Travel and Geographic Medicine
Sheba Medical Center
研究点 (2)
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