The effect of yarrow vaginal cream on treatment of candida vaginitis
Phase 2
Recruiting
- Conditions
- Candida vulvovaginitis.Candidiasis of vulva and vagina
- Registration Number
- IRCT20170918036261N1
- Lead Sponsor
- Vice chancellor for research Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
married women,18 to 45 years old
The presence of sign and symptoms of candida vulvovaginitis
Positive smear from vaginal discharge for candida
Positive culture of vaginal discharge for candida
Exclusion Criteria
History of allergy to clotrimazole vaginal cream
History of drug allergy
Pregnancy
Mensturation period
Breastfeeding
Menopause
The presence of chronic underlying diseases: kidney, liver and Heart diseases, Diabetes and Immune deficiency
Score 24-30 based on DLQI questionnaire
Vulvar erythem score 3
Use of systemic antibiotics, immunosuppressive drugs or other vaginal creams and antifungal drugs during the past 4 weeks
Patient's unsatisfactory to participate in the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Burning. Timepoint: At first, 7-10 days after the beginning of interventon and 2-3 weeks after the end of intervention. Method of measurement: Evauation of clinical symptom's remission (burning) with Dermatology Quality of Life Index (DLQI ) questionnaire.;Pruritus. Timepoint: At first, 7-10 days after the begining of interventon and 2-3 weeks after the end of intervention. Method of measurement: Evauation of clinical symptom's remission (pruritus) with Dermatology Quality of Life Index (DLQI ) questionnaire.;Dysparonia. Timepoint: At first, 7-10days after the begining of interventon and 2-3 weeks at the end of intervention. Method of measurement: Evauation the rate of satisfactory from intercourse with Dermatology Quality of Life Index (DLQI ) questionnaire.;Volvar erythema. Timepoint: At first, 7-10days after the begining of interventon and 2-3 weeks at the end of intervention. Method of measurement: Vulvar examination and scoring the erythema of vulva by Gynecologist.
- Secondary Outcome Measures
Name Time Method Result of culture. Timepoint: At first, 7-10 days after the begining of intervention and 2-3 weeks after the end of intervention. Method of measurement: Sampling from vaginal discharges.