Evaluation of the diagnosis accuracy and eradication protocol of Helicobacter pylori gastritis in CKD 5 hemodialysis patients
Phase 4
- Conditions
- Hemodialysis patients with Helicobacter pylori gastritis
- Registration Number
- JPRN-UMIN000013660
- Lead Sponsor
- Division of Clinical Nephrology & Rheumatology, Niigata University Graduate School of Medical & Dental Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients with a history of hypersensitivity for amoxicillin, clarithromycin, proton pump inhibitors, or metronidazole. 2) Of the patients with CKD, the patient being predicted for initiating dialysis within six months. 3) Patients complicated with acute inflammatory disease or active infection. 4) Patients with active malignant tumor. 5) Patients who suspected of being pregnant or pregnancy. 6) Patients did not make a consent for test and/or treatment of H. pyroli gastritis. 7) Patients was determined to be difficult to continue the eradication therapy by serious adverse events. 8) Patients offer discontinuation of the study. 9) Attending physician deems the patients as unsuitable of the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eradication rate for Helicobacter pyroli
- Secondary Outcome Measures
Name Time Method Sensitivity and specificity of anti-Helicobacter pylori Antibody-IgG, Dry weight during dialysis, blood pressure, body weight, chest X-ray CTR, hemoglobin, dose of ESA, serum iron, UIBC (not to TIBC), ferritin, CRP.