Ultrasonography Guided Brain Lesions Resection: a Tool for a Real Time Intraoperative Neuronavigation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Patients Who Are Diagnosed to Have Intracranial Lesions
- Sponsor
- Assiut University
- Enrollment
- 1
- Primary Endpoint
- Extent of resection of the lesion
- Last Updated
- 5 years ago
Overview
Brief Summary
- Evaluate the clinical value of intraoperative ultrasonography as a real-time guidance
- Combination of data of MRI Tractography and intra operative ultrasonography will be useful in good localization of lesions or not .
- Maximal safe resection .
Detailed Description
Accurate pre and intraoperative localization of Brain lesions is a challenge in neurosurgery specially deep intra cerebral lesions. Stereotaxy and neuronavigator played a major role in preoperative and intraoperative evaluation of exact location of intra cerebral lesions, the main drawbacks of using steriotaxy and neuronavigator that they are time consuming, complicated and expensive.(1) Nowadays we use MRI Tractography as preoperative imaging to localize lesions and there relation to neural tracts specially in eloquent brain areas, and also intraoperative ultrasonography Which act as a real-time, unexpansive and relatively simple tool for intraoperative visualization of the lesion's location, size, extent and its relationship with the surrounding tissue, also it can reveal the lesion's blood supply, it can measure the rate and direction of arterial blood flow.(2,3,4) Intraoperative ultrasonic imaging was first applied as a real-time navigation system in neurosurgery in 1980. (5) In this research we will combine the use of preoperative MRI tractography with intra operative ultrasonography in accurate localization of brain lesions and its relation with important tracts and if this combination will be beneficial and add to the safety of excision of lesions or not.
Investigators
Sarah Ahmed Saad
resident doctor, neurosurgery department
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Patients who are diagnosed to have Intracranial lesions Patients with recurrent lesions
Exclusion Criteria
- •Patients who are unfit for surgery Patients who have multifocal lesions
Outcomes
Primary Outcomes
Extent of resection of the lesion
Time Frame: 48 hours
Extent of resection of the lesion evaluated by comparing pre operative and post operative MRI
Secondary Outcomes
- post operative complication(one month)