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Clinical Trials/NCT04569526
NCT04569526
Unknown
Not Applicable

Ultrasonography Guided Brain Lesions Resection: a Tool for a Real Time Intraoperative Neuronavigation

Assiut University0 sites1 target enrollmentSeptember 25, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Patients Who Are Diagnosed to Have Intracranial Lesions
Sponsor
Assiut University
Enrollment
1
Primary Endpoint
Extent of resection of the lesion
Last Updated
5 years ago

Overview

Brief Summary

  1. Evaluate the clinical value of intraoperative ultrasonography as a real-time guidance
  2. Combination of data of MRI Tractography and intra operative ultrasonography will be useful in good localization of lesions or not .
  3. Maximal safe resection .

Detailed Description

Accurate pre and intraoperative localization of Brain lesions is a challenge in neurosurgery specially deep intra cerebral lesions. Stereotaxy and neuronavigator played a major role in preoperative and intraoperative evaluation of exact location of intra cerebral lesions, the main drawbacks of using steriotaxy and neuronavigator that they are time consuming, complicated and expensive.(1) Nowadays we use MRI Tractography as preoperative imaging to localize lesions and there relation to neural tracts specially in eloquent brain areas, and also intraoperative ultrasonography Which act as a real-time, unexpansive and relatively simple tool for intraoperative visualization of the lesion's location, size, extent and its relationship with the surrounding tissue, also it can reveal the lesion's blood supply, it can measure the rate and direction of arterial blood flow.(2,3,4) Intraoperative ultrasonic imaging was first applied as a real-time navigation system in neurosurgery in 1980. (5) In this research we will combine the use of preoperative MRI tractography with intra operative ultrasonography in accurate localization of brain lesions and its relation with important tracts and if this combination will be beneficial and add to the safety of excision of lesions or not.

Registry
clinicaltrials.gov
Start Date
September 25, 2020
End Date
December 30, 2021
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sarah Ahmed Saad

resident doctor, neurosurgery department

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Patients who are diagnosed to have Intracranial lesions Patients with recurrent lesions

Exclusion Criteria

  • Patients who are unfit for surgery Patients who have multifocal lesions

Outcomes

Primary Outcomes

Extent of resection of the lesion

Time Frame: 48 hours

Extent of resection of the lesion evaluated by comparing pre operative and post operative MRI

Secondary Outcomes

  • post operative complication(one month)

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