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临床试验/NCT04569526
NCT04569526Unknown不适用

Ultrasonography Guided Brain Lesions Resection: a Tool for a Real Time Intraoperative Neuronavigation

Assiut University0 个研究点目标入组 1 人开始时间: 2020年9月25日最近更新:
适应症

试验速览

阶段
不适用
入组人数
1
主要终点
Extent of resection of the lesion

研究概览

简要总结

  1. Evaluate the clinical value of intraoperative ultrasonography as a real-time guidance
  2. Combination of data of MRI Tractography and intra operative ultrasonography will be useful in good localization of lesions or not .
  3. Maximal safe resection .

详细描述

Accurate pre and intraoperative localization of Brain lesions is a challenge in neurosurgery specially deep intra cerebral lesions. Stereotaxy and neuronavigator played a major role in preoperative and intraoperative evaluation of exact location of intra cerebral lesions, the main drawbacks of using steriotaxy and neuronavigator that they are time consuming, complicated and expensive.(1) Nowadays we use MRI Tractography as preoperative imaging to localize lesions and there relation to neural tracts specially in eloquent brain areas, and also intraoperative ultrasonography Which act as a real-time, unexpansive and relatively simple tool for intraoperative visualization of the lesion's location, size, extent and its relationship with the surrounding tissue, also it can reveal the lesion's blood supply, it can measure the rate and direction of arterial blood flow.(2,3,4) Intraoperative ultrasonic imaging was first applied as a real-time navigation system in neurosurgery in 1980. (5) In this research we will combine the use of preoperative MRI tractography with intra operative ultrasonography in accurate localization of brain lesions and its relation with important tracts and if this combination will be beneficial and add to the safety of excision of lesions or not.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
1 Month 至 70 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who are diagnosed to have Intracranial lesions Patients with recurrent lesions

排除标准

  • Patients who are unfit for surgery Patients who have multifocal lesions

结局指标

主要结局

Extent of resection of the lesion

时间窗: 48 hours

Extent of resection of the lesion evaluated by comparing pre operative and post operative MRI

次要结局

  • post operative complication(one month)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sarah Ahmed Saad

resident doctor, neurosurgery department

Assiut University

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