Correlation Between Salivary Immuno Biochemical Markers And Hb1ac in type 2 Diabetes subjects Before And After Dental Extraction.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Finding the Correlation Between Salivary Immuno Biochemical Markers And Hb1ac.
研究概览
简要总结
This study demonstrates a significant correlation between salivary biochamical markers and Hba1c levels in type 2 diabetes subjects before after dental extraction. the finding suggest that
1 salivary biomarkers
Certain biomarkers OPG RANKL TNF@ MMP9 IL18 in saliva may serve as potential indicators of glycemic control in type 2 diabetes patients.
2 Dental extraction impact
dental extraction may influence salivary biochemical markers levels, potentially reflecting chenges in stress inflammation or glycemic control.
3 Hb1ac correlation
The correlation between salivary biochemical markers and Hb1ac levels highlights the potential for salivary diagnostic to monitor glycemic control in type 2 diabetes patients.
CLINICAL IMPLICATION
1 Non invasive monitoring
salivary biomarkers may offer a non invasive , convenient method for monitoring glycemic control
2 Dental care optimization
Understanding the impact of dental procedure on salivary biochemical markers can help optimize dental care for type 2 diabetes patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients Who require atleast one tooth extraction With a Definite Diagnosis of Type 2 Diabetes For At Least 3 Years With Glycated Hemoglobin Values Between 6.5% and 11%.
排除标准
- •Use of antibiotic or anti-inflammatory therapy in the last 3 months.
- •Any periodontal or orthodontic treatment in the last 6 months.
- •Periodontal disease stage 3 or
- •Body mass index (BMI) 30, psychiatric disorders, pregnant or lactating women, Smokers, systemic diseases that may interfere with the immune response, or with bone metabolism (osteoporosis, rheumatoid arthritis, endocrine diseases, etc.) Except for diabetes type 2.
结局指标
主要结局
Finding the Correlation Between Salivary Immuno Biochemical Markers And Hb1ac.
时间窗: Before Extraction And 3 Months After Extraction
次要结局
未报告次要终点
研究者
Dr Larensh Kumar
Institute of Dental Studies and Technologies Modinagar