MedPath

Observational Study to Investigate the Occurrence of Bleeding in Postmenopausal Women Treated With Estradiol/NETA for 12 Months

Completed
Conditions
Menopause
Postmenopausal Bleeding
Interventions
Registration Number
NCT01076621
Lead Sponsor
Novo Nordisk A/S
Brief Summary

This study is conducted in Europe. The primary aim of this observational study is to investigate the occurrence of bleeding in women taking 0.5 mg estradiol and 0.1 mg norethisterone acetate (NETA) for 12 months.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
176
Inclusion Criteria
  • Informed consent, permitting the data to be processed within the scope of the study, is obtained from the patient before any study-related activities
  • Postmenopausal amenorrhoeic women
  • Treatment with previously combined HRT discontinued at least 3 months prior to start of 0.5 mg estradiol and 0.1 mg norethisterone acetate treatment
Read More
Exclusion Criteria

Not provided

Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
A0.5 mg estradiol / 0.1 mg norethisterone acetate (NETA)-
Primary Outcome Measures
NameTimeMethod
Bleeding profile during the 52 weeks of treatment with 0.5 mg estradiol and 0.1 mg norethisterone acetate evaluated by bleeding, and bleeding or spotting ratesAt every lunar month (28 days)
Secondary Outcome Measures
NameTimeMethod
Change in bleeding profileDuring the 52 weeks of treatment
Change in mean number of hot flushes per weekDuring the 52 weeks of treatment
© Copyright 2025. All Rights Reserved by MedPath