跳至主要内容
临床试验/NCT05571228
NCT05571228进行中(未招募)不适用

Be Outspoken and Overcome Stigmatizing Thoughts (BOOST) Group for Early Psychosis

Queen's University2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2020年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
100
试验地点
2
主要终点
Internalized stigma

研究概览

简要总结

Internalized stigma, (i.e. the application of negative stereotypes about a diagnostic group to one's self) is a strong predictor of recovery and quality of life for individuals with psychosis. Be Outspoken and Overcome Stigmatizing Thoughts (BOOST) is an evidence-based intervention aimed at improving internalized stigma, self-esteem, and quality of life for those with psychosis. The proposed research expands BOOST's program by adding additional therapeutic methods and material, and adopting the use of virtual care methods to: (a) increase the generalization of treatment effects, (b) examine long-term treatment effects, and (C) provide rural Ontario communities with remote treatment access.

详细描述

Internalized stigma, defined as the application of negative stereotypes about a diagnostic group to one's self, is a strong predictor of quality of life and recovery in schizophrenia and other psychoses, accounting for over half the variance. However, few effective interventions for self-stigma have been developed and even fewer individuals have access to these services.

Be Outspoken and Overcome Stigmatizing Thoughts (BOOST) is an evidence-based intervention developed by the research team that has significantly improved internalized stigma, self-esteem, and quality of life for young people with psychosis. This group therapy was co-created and is co-facilitated by people with lived experience with psychosis specifically for the early psychosis population. The proposed research expands this intervention by examining the efficacy of group delivery through virtual methods that could allow us to reach individuals that are unlikely to attend regular in-person sessions for a variety of reasons.

Psychotic disorders are among the most highly stigmatized mental health conditions. Over 50% of individuals with schizophrenia and other psychoses report significant internalization of these stigmatizing attitudes. Internalized stigma is defined as the application of societally held stereotypes about the illness to one's self. It is associated with a broad array of significant psychosocial consequences including reduced social functioning, isolation, and reduced rates of recovery. Internalized stigma is also associated with serious decrements in self-esteem, self-efficacy, and hope. Reducing internalized stigma has been recognized as such a critical factor in recovery from psychosis that both the World Health Organization and National Institute for Health and Care Excellence prioritize the reduction of stigma to improve recovery from psychosis.

Despite the clear importance of reducing internalized stigma in psychosis, few interventions have been developed to reduce internalized stigma about mental illness. Only a single intervention had previously been developed to specifically reduce internalized stigma among individuals in the early stages of psychosis. None of these internalized stigma interventions have demonstrated strong evidence for efficacy. The current approaches to reducing internalized stigma have focused almost exclusively on psychoeducation about psychosis, without evidence-based therapeutic techniques, and with treatment later in illness, when self-stigma has already set in. The investigators developed Be Outspoken and Overcome Stigmatizing Thoughts (BOOST), a group-based intervention integrating cognitive behavioural therapy (CBT) and peer support to reduce or prevent the internalization of stigma in early psychosis. Peer support is an especially important intervention for psychosis as peer support workers provide personal examples to normalize experiences that clients are having. Peer support has been demonstrated to improve social functioning and recovery for individuals with psychosis. Thus, the investigators propose that the combination of these approaches would be ideal to reduce internalized stigma.

In the initial pilot study[13], BOOST demonstrated significant improvements in internalized stigma, self-esteem, and quality of life. Despite BOOST demonstrating the largest effect size improvement on internalized stigma of any intervention currently evaluated (Cohen's d = 0.76), this was a small non-randomized sample, so the investigators would like to build the evidence base for the intervention and examine the breadth of treatment effects.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of schizophrenia, schizoaffective disorder or any other psychotic disorder
  • Must be 18-35 years of age
  • Know how to use a computer and telephone
  • Not abusing drugs or alcohol
  • Can read and speak English

排除标准

  • Individuals enrolled in a cognitive behavioural therapy program in the last 6 months
  • Individuals with neurological disease or neurological damage
  • Individuals with medical illnesses that can change neurocognitive function
  • Individuals with a medical history of a head injury with loss of consciousness
  • Physical handicaps that would prevent an individual from engaging in the BOOST program

结局指标

主要结局

Internalized stigma

时间窗: Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.

This project will assess how virtual BOOST treatment changes psychological factors associated with recovery. The primary outcome measure is internalized stigma as measured by the Internalized Stigma of Mental Illness Scale.

次要结局

  • Patient Health Questionnaire(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)
  • Interpersonal Needs Questionnaire(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)
  • Self-Injurious Thoughts and Behaviours Interview Self-Report(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)
  • Rosenberg Self-Esteem Scale(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)
  • Psychache Scale(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)
  • Generalized Anxiety Disorder scale (GAD-7)(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)
  • Interpersonal Hopelessness Scale(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)
  • Satisfaction with Life Scale(Participants will be assessed at baseline, and assessed for changes immediately following the treatment and at 6 months and 12 months post treatment.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Christopher Bowie

Professor and Director of Clinical Training Department with the Psychology

Queen's University

研究点 (2)

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