Role of yoga in patients with heart attack

Completed

• Conditions: Acute myocardial infarction, unspecified, Myocardial Infarction,

• Registration Number: CTRI/2017/09/009925
• Lead Sponsor: All India Institute of Medical Sciences

Brief Summary

The therapeutic landscapes of yoga are diverse. Several studies have shown that yoga and meditation control risk factors for cardiovascular disease like hypertension, type II diabetes and insulin resistance, obesity, lipid profile, psychosocial stress and smoking. Some randomized studies suggest that yoga / meditation could retard or even regress early and advanced coronary atherosclerosis.

CR is the process of restoring desirable levels of physical, social, and psychological functioning after the onset of cardiovascular illness. The aims of CR programmes are to optimise patient’s functioning, enhance quality of life, and minimise the risk of recurrent cardiac events. Comprehensive CR programmes are multi-component interventions, which include elements of exercise training, relaxation and stress management, secondary prevention, and pay attention to the patient’s psychosocial adjustment.  Yoga covers most of the elements of a comprehensive CR programme: improved physical fitness, stress reduction and lifestyle. The proposed research is to understand the mechanism behind the effects of Yoga based cardiac rehabilitation on autonomic, vascular and endothelial functions in patients following Acute Myocardial Infarction. Most of the studies on yoga are limited to healthy subjects and diseased conditions other than myocardial infarction. This study is unique in that there is deficiency of data on the effect of yoga based cardiac rehabilitation in acute Myocardial infarction patients. Therefore, this study proposes to test the mechanisms underlying the effects of Yoga-Cardiac Rehabilitation program in patients with acute myocardial infarction to suggest a road map for future enhancement of Yoga based Cardiac rehabilitation.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05-16
• Study Completion: 2017-06-22
• Last Update Posted: 2022-03-30

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients with MI 2.
• Willingness to attend the yoga sessions.

Exclusion Criteria

• Patients who regularly practice yoga 2.
• Current participation in other clinical trials 3.
• Severe valvular diseases, arrhythmias, heart failure (Killip class IV), end stage renal diseases and end stage liver diseases.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart rate variability (HRV),	Baseline - 3 weeks post MI | Intervention - 3 Months | Post intervention - at the end of 3rd month | follow up - 3 months after intervention
Blood Pressure Variability (BPV),	Baseline - 3 weeks post MI | Intervention - 3 Months | Post intervention - at the end of 3rd month | follow up - 3 months after intervention
Baroreflex Sensitivity (BRS), Pulse wave velocity (PWV),	Baseline - 3 weeks post MI | Intervention - 3 Months | Post intervention - at the end of 3rd month | follow up - 3 months after intervention
Augmentation Index (AIx), Flow mediated dilatation (FMD)	Baseline - 3 weeks post MI | Intervention - 3 Months | Post intervention - at the end of 3rd month | follow up - 3 months after intervention

Secondary Outcome Measures

Name	Time	Method
Echocardiography	Baseline - 3 weeks post MI

Trial Locations

Locations (1)

AIIMS; 🇮🇳 South, DELHI, India

AIIMS

🇮🇳South, DELHI, India

S Edmin Christa

Principal investigator

8373961624

drchristabnys@gmail.com