Effect of transdermal testosterone replacement in hypogonadal men with decreased insulin sensitivity

Completed

• Conditions: Hypogonadal men with decreased insulin sensitivity; Nutritional, Metabolic, Endocrine; Testicular hypofunction

• Registration Number: ISRCTN45741714
• Lead Sponsor: ProStrakan Pharmaceuticals (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-02-06
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 320

Inclusion Criteria

1.Hypogonadal males

2.Decreased insulin sensitivity

Exclusion Criteria

1.Use of testosterone replacement therapy in the last six months

2.History of or current prostate carcinoma

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in insulin sensitivity

Secondary Outcome Measures

Name	Time	Method
1.Change in abdominal obesity, lipid profile and glycaemic control<br><br>2.Change in symptoms of hypogonadism<br><br>3.The safety and tolerability of testosterone replacement gel compared to placebo gel